2014年以前

2014年以前

1. Synthesis and Biological Activity of 1α,2α,25-Trihydroxyvitamin D3: Active Metabolite of 2α-(3-Hydroxypropoxy)-1α,25-dihydroxyvitamin D3 by HumanCYP3A4.
   Takano M, Ohya S, Yasuda K, Nishikawa M, Takeuchi A, Sawada D, Sakaki T, Kittaka A.
   Chem Pharm Bull. 62:182-4. (2014)
   
   
2. Anti-proliferative activity of 25-hydroxyvitamin D3 in human prostate cells.
   Munetsuna E, Kawanami R, Nishikawa M, Ikeda S, Nakabayashi S, Yasuda K, Ohta M, Kamakura M, Ikushiro S, Sakaki T.
   Mol Cell Endocrinol. 382:960-70. (2014)
   
   
3. 7-Dehydrocholesterol metabolites produced by sterol 27-hydroxylase (CYP27A1) modulate liver X receptor activity.
   Endo-Umeda K, Yasuda K, Sugita K, Honda A, Ohta M, Ishikawa M, Hashimoto Y, Sakaki T, Makishima M.
   J Steroid Biochem Mol Biol. 140:7-16. (2014)
   
   
4. ヒト由来CYP2R1 発現酵母を用いた25-ヒドロキシビタミンD2 の生産.
   安田佳織，遠藤真理子，小又早紀，生城真一，鎌倉昌樹，太田美穂，榊利之;
   日本ビタミン学会誌, 88:451-457 (2014)
   
   
5. CYP24A1 as a Potential Target for Cancer Therapy.
   Sakaki T, Yasuda K, Kittaka A, Yamamoto K, Chen TC.
   Anticancer Agents Med Chem. 14:97-108. (2014)
   
   
6. UV-dependent production of 25-hydroxyvitamin D2 in the recombinant yeast cells expressing human CYP2R1.
   Yasuda K, Endo M, Ikushiro S, Kamakura M, Ohta M, Sakaki T.
   Biochem Biophys Res Commun. 434:311-315. (2013)
   
   
7. 1,25(OH)2D-24 Hydroxylase (CYP24A1) Deficiency as a Cause of Nephrolithiasis.
   Nesterova G, Malicdan MC, Yasuda K, Sakaki T,
   Vilboux T, Ciccone C, Horst R, Huang Y, Golas G, Introne W, Huizing M, Adams D, Boerkoel CF, Collins MT, Gahl WA.Clin J Am Soc Nephrol. 8: 649-657 (2013)
   
   
8. Human cytochrome P450-dependent differential metabolism among three 2α-substituted 1α,25-dihydroxyvitamin D3 analogs.
   Yasuda K, Ikushiro S, Kamakura M, Takano M, Saito N, Kittaka A, Chen TC, Ohta M, Sakaki T;
   J Steroid Biochem Mol Biol. 133: 84-92. (2013)
   
   
9. 1α,4α,25- and 1α,4β,25-Trihydroxyvitamin D3 and their metabolism by human CYP24A1 and UDP-glucuronosyltransferase.
   Sawada D, Tsukuda Y, Yasuda K, Sakaki T, Saito H, Takagi K, TakenouchiK, Chen TC, Reddy GS, Kittaka A;
   Synthesis and biological activities of Chem. Pharm. Bull. 60:1343-1346. (2012)
   
   
10. Comparison of metabolism of sesamin and episesamin by drug metabolizing enzymes in human liver.
    Yasuda K, Ikushiro S, Wakayama S, Itoh T, Yamamoto K, Kamakura M, Munetsuna E, Ohta M, Sakaki T.
    Drug Metab Dispos. 40:1917-26. (2012)
    
    
11. How is sesamin metabolised in the human liver to show its biological effects?
    Yasuda K, Sakaki T.
    Expert Opin Drug Metab Toxicol. 8:93-102 (2012)
    
    
12. Metabolism of Sesamin by CYPs and UGTs in Human Liver.
    Sakaki T, Yasuda K, Kamakura M, Munetsuna E, Ohta M, Ikushiro S
    Journal of Food and Drug Analysis, 20:376-379 (2012)
    
    
13. Mechanism of the anti-proliferative action of 25-hydroxy-19-nor-vitamin D3 in human prostate cells
    Munetsuna E, Nakabayashi S, Kawanami R, Yasuda K, Ohta M, Arai MA, Kittaka A, Chen TC, Kamakura M, Ikushiro S, Sakaki T
    J Mol Endocrinol. 47:209-18. (2011)
    
    
14. Sequential metabolism of sesamin by cytochrome P450 and UDP-glucuronosyltransferase in human liver.
    Yasuda K, Ikushiro S, Kamakura M, Munetsuna E, Ohta M, Sakaki T.
    Drug Metab Dispos. 39:1538-45 (2011)
    
    
15. Bioconversion of vitamin D to its active form by bacterial or mammalian cytochrome P450.
    Sakaki T, Sugimoto H, Hayashi K, Yasuda K, Munetsuna E, Kamakura M, Ikushiro S, Shiro Y;
    Biochim Biophys Acta. 1814:249-56 (2011)
    
    
16. CYP105A1 二重変異体を発現する放線菌を用いた活性型ビタミンD3 の生産.
    安田佳織，林恵子，生城真一，鎌倉昌樹，宗綱栄二, 杉本宏, 城宜嗣，橘高敦史，太田美穂，榊利之;
    日本ビタミン学会誌, 85:47-52 (2011)
    
    
17. Studies on the synthesis and metabolism of 14-epi-2-(3-hydroxypropyl)-19-norvitamin D3 and its 2-isomer.
    Kittaka A, Hara H, Yasuda K, Takano M, Arai AM, Sawada D, Saito H, Takenouchi K, Chen TC, Sakaki T
    HETEROCYCLES, 82:649-661 (2010)
    
    
18. Metabolism of sesamin by cytochrome P450 in human liver microsomes.
    Yasuda K, Ikushiro S, Kamakura M, Ohta M, Sakaki T
    Drug Metab Dispos. 38:2117-23 (2010)
    
    
19. Three-step hydroxylation of vitamin D3 by a genetically engineered CYP105A1: Enzymes and catalysis.
    Hayashi K, Yasuda K, Sugimoto H, Ikushiro S, Kamakura M, Kittaka A, Horst RL, Chen TC, Ohta M, Shiro Y, Sakaki T
    FEBS J. 277:3999-4009 (2010)
    
    
20. Metabolism of mono- and dichloro-dibenzo-p-dioxins by phanerochaete chrysosporium cytochromes P450.
    Kasai N, Ikushiro S, Shinkyo R, Yasuda K, Hirosue S, Arisawa A, Ichinose H, Wariishi H, Sakaki T
    Appl Microbiol Biotechnol. 86:773-80 (2010)
    
21. Synthesis of 2α-propoxy-1α,25-dihydroxyvitamin D3 and comparison of its metabolism by human CYP24A1 and rat CYP24A1.
    Saito N, Suhara Y, Abe D, Kusudo T, Ohta M, Yasuda K, Sakaki T, Honzawa S, Fujishima T, Kittaka A
    Bioorg Med Chem. 17:4296-301 (2009)
    
    
22. Metabolism of 1alpha,25-dihydroxyvitamin D2 by human CYP24A1.
    Urushino N, Yasuda K, Ikushiro S, Kamakura M, Ohta M, Sakaki T
    Biochem Biophys Res Commun. 384:144-8. (2009)
    
    
23. Expression of Clostridium acetobutylicum butanol synthetic genes in Escherichia coli
    Inui M, Suda M, Kimura S, Yasuda K, Suzuki H, Toda H, Yamamoto S, Okino S, Suzuki N and Yukawa H
    Appl Microbiol Biotechnol. 77:1305-16 (2008)
    
    
24. Analyses of the acetate-producing pathways in Corynebacterium glutamicum under oxygen-deprived conditions
    Yasuda K, Jojima T, Suda M, Okino S, Inui M and Yukawa H
    Appl Microbiol Biotechnol. 77:853-60 (2007)
    
    
25. Formation of Poly(vinyl alcohol)-Titanium Lactate Hybrid Nanofibers and Properties of TiO2 Nanofibers Obtained by Calcination of the Hybrids.
    Nakane K, Yasuda K, Ogihara T, Ogata N, Yamaguchi S
    Journal of Applied Polymer Science, 104:1232–1235 (2007)
    
    
26. Cell attachment to PET films coated with a thermo-sensitive block co-polymer
    with different chemical composition.
    Takamoto T, Yasuda K, Tsujino T, Sugihara S, Kanaoka S, Aoshima S, Tabata Y
    J Biomater Sci Polym Ed. 18:1211-1222 (2007)
    
    
27. In situ regeneration of adipose tissue in rat fat pad by combining a collagenscaffold with gelatin microspheres containing basic fibroblast growth factor
    Hiraoka Y, Yamashiro H, Yasuda K, Kimura Y, Inamoto T, Tabata Y;
    Tissue Engineering, 12:1475-1487 (2006)
    
    
28. Influence of culture method on the proliferation and osteogenic differentiation of human adipo-stromal cells in non-woven fabrics.
    Yasuda K, Inoue S, and Tabata Y
    Tissue Engineering, 10:1587-1596 (2004)